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Skip to content AboutNews/In the MediaSiteman Cancer Center ranked No. 10 among U.S. cancer centersSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine has been named No. 10 among cancer centers nationally by U.S. News & World Report. The recognition is part of the overall ranking…Read The Full Story Mission, Vision & History Why Siteman Diversity, Equity & Inclusion at SitemanAboutDiversity, Equity & Inclusion at SitemanLearn More Leadership Organizations Committees Partnerships Contact This is Cancer Learning With National Leaders In the News TreatmentClinicalHow Siteman is leading the way in personalized brain tumor treatmentIf you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,…Read The Full Story Physician Directory Clinical Trials Search Patient Experience Siteman Psychology Service Survivorship Cardio-Oncology Lymphedema Surgery NCI Cancer Information A to Z Treatment Roles Cancer Types Bladder Brain Breast Cervical Childhood Cancers Colorectal Young Onset Colorectal Esophageal Gallbladder Head/Neck Kidney Leukemia Liver Lung Lymphoma Multiple Myeloma Myelodysplastic Syndromes (MDS) Ovarian Pancreatic Prostate Sarcoma/Rare Tumors Skin Stomach Testicular Thyroid Uterine The Siteman Approach Medical Therapy Expertise in Radiation Oncology Surgery Genetics and Hereditary Cancer Cancer Imaging Immunology and Immunotherapy Pathology Patient and Family Services Specialized Programs Stem Cell Transplant and Cellular Therapies Center Gynecologic Oncology Brain Tumor Center Sarcoma VisitingNews/In the MediaSiteman Cancer Center expands proton therapy treatmentSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is expanding proton therapy for patients by adding the latest, most innovative technology to its S. Lee Kling Proton Therapy Center with the addition of…Read The Full Story Patient and Family Services Washington University Medical Campus West County St. Charles County South County Siteman Kids at St. Louis Children’s Hospital North County Illinois Siteman Cancer Network Cancer Care Clinic Barnard Health and Cancer Information Center Pharmacies Payment Information & Assistance Patient Rights Patient Privacy PreventionPreventionSiteman explains what every woman should know about endometrial cancer risk, symptoms and screeningEndometrial cancer is the fourth most common cancer for women in the United States. It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is…Read The Full Story Your Disease Risk® Preventing Cancer Risk Factors Screening Smoking Cessation Mammography Genetic Counseling Cancer News in Context 8IGHTWAYS® to Prevent Cancer Health Disparities Community Outreach and Engagement ResearchResearchImmunity boosting treatment enhances CAR-T cell therapy for blood cancersAdvances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug Administration…Read The Full Story List of Researchers Significant Research Advances Learn About Clinical Trials Membership Information Plan to Enhance Diversity (PED) Research Programs Funding Opportunities Training & Education Shared Resources (Cores) Resources for Researchers SPORE in Pancreatic Cancer SPORE in Endometrial Cancer SPORE in Leukemia Center for Genome Integrity CliniciansNews/In the Media$5.3 million grant supports research into lung cancer recurrenceResearchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after…Read The Full Story Physician Services Educational Programs GiveNews/In the MediaCouple honors physician with gift for distinguished professorshipEndowment will support leader in gynecologic oncology Financial adviser Elizabeth Mannen Berges lives each day with heightened gratitude for the basic components of a meaningful life—fulfilling work, caring relationships, and a sense of purpose. A…Read The Full Story Siteman Advancement Office Volunteering and Contributing The Foundation for Barnes-Jewish Hospital AboutNews/In the MediaSiteman Cancer Center ranked No. 10 among U.S. cancer centersSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine has been named No. 10 among cancer centers nationally by U.S. News & World Report. The recognition is part of the overall ranking...Read The Full StoryAboutNews/In the MediaSiteman Cancer Center ranked No. 10 among U.S. cancer centersSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine has been named No. 10 among cancer centers nationally by U.S. News & World Report. The recognition is part of the overall ranking...Read The Full StoryMission, Vision & HistoryWhy SitemanDiversity, Equity & Inclusion at SitemanAboutDiversity, Equity & Inclusion at SitemanLearn MoreLeadershipOrganizationsCommitteesPartnershipsContactThis is CancerLearning With National LeadersIn the NewsTreatmentClinicalHow Siteman is leading the way in personalized brain tumor treatmentIf you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,...Read The Full StoryTreatmentClinicalHow Siteman is leading the way in personalized brain tumor treatmentIf you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,...Read The Full StoryPhysician DirectoryClinical Trials SearchPatient ExperienceSiteman Psychology ServiceSurvivorshipCardio-OncologyLymphedema SurgeryNCI Cancer Information A to ZTreatment RolesCancer TypesCancer TypesBladderBrainBreastCervicalChildhood CancersColorectalYoung Onset ColorectalEsophagealGallbladderHead/NeckKidneyLeukemiaLiverLungLymphomaMultiple MyelomaMyelodysplastic Syndromes (MDS)OvarianPancreaticProstateSarcoma/Rare TumorsSkinStomachTesticularThyroidUterineThe Siteman ApproachThe Siteman ApproachMedical TherapyExpertise in Radiation OncologySurgeryGenetics and Hereditary CancerCancer ImagingImmunology and ImmunotherapyPathologyPatient and Family ServicesSpecialized ProgramsSpecialized ProgramsStem Cell Transplant and Cellular Therapies CenterGynecologic OncologyBrain Tumor CenterSarcomaVisitingNews/In the MediaSiteman Cancer Center expands proton therapy treatmentSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is expanding proton therapy for patients by adding the latest, most innovative technology to its S. Lee Kling Proton Therapy Center with the addition of...Read The Full StoryVisitingNews/In the MediaSiteman Cancer Center expands proton therapy treatmentSiteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine is expanding proton therapy for patients by adding the latest, most innovative technology to its S. Lee Kling Proton Therapy Center with the addition of...Read The Full StoryPatient and Family ServicesWashington University Medical CampusWest CountySt. Charles CountySouth CountySiteman Kids at St. Louis Children’s HospitalNorth CountyIllinoisSiteman Cancer NetworkCancer Care ClinicBarnard Health and Cancer Information CenterPharmaciesPayment Information & AssistancePatient RightsPatient PrivacyPreventionPreventionSiteman explains what every woman should know about endometrial cancer risk, symptoms and screeningEndometrial cancer is the fourth most common cancer for women in the United States. It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is...Read The Full StoryPreventionPreventionSiteman explains what every woman should know about endometrial cancer risk, symptoms and screeningEndometrial cancer is the fourth most common cancer for women in the United States. It also accounts for approximately 4 percent of cancer deaths in women. However, because it is usually diagnosed early, it is...Read The Full StoryYour Disease Risk®Preventing CancerRisk FactorsScreeningSmoking CessationMammographyGenetic CounselingCancer News in Context8IGHTWAYS® to Prevent CancerHealth DisparitiesCommunity Outreach and EngagementResearchResearchImmunity boosting treatment enhances CAR-T cell therapy for blood cancersAdvances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug Administration...Read The Full StoryResearchResearchImmunity boosting treatment enhances CAR-T cell therapy for blood cancersAdvances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers. Six such CAR-T cell therapies are approved by the Food and Drug Administration...Read The Full StoryList of ResearchersSignificant Research AdvancesLearn About Clinical TrialsMembership InformationPlan to Enhance Diversity (PED)Research ProgramsFunding OpportunitiesTraining & EducationShared Resources (Cores)Resources for ResearchersSPORE in Pancreatic CancerSPORE in Endometrial CancerSPORE in LeukemiaCenter for Genome IntegrityCliniciansNews/In the Media$5.3 million grant supports research into lung cancer recurrenceResearchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after...Read The Full StoryCliniciansNews/In the Media$5.3 million grant supports research into lung cancer recurrenceResearchers at Washington University School of Medicine in St. Louis are leading a national study aimed at identifying patients with early-stage lung cancer who are at high risk of having the cancer return, even after...Read The Full StoryPhysician ServicesEducational ProgramsGiveNews/In the MediaCouple honors physician with gift for distinguished professorshipEndowment will support leader in gynecologic oncology Financial adviser Elizabeth Mannen Berges lives each day with heightened gratitude for the basic components of a meaningful life—fulfilling work, caring relationships, and a sense of purpose. A...Read The Full StoryGiveNews/In the MediaCouple honors physician with gift for distinguished professorshipEndowment will support leader in gynecologic oncology Financial adviser Elizabeth Mannen Berges lives each day with heightened gratitude for the basic components of a meaningful life—fulfilling work, caring relationships, and a sense of purpose. A...Read The Full StorySiteman Advancement OfficeVolunteering and ContributingThe Foundation for Barnes-Jewish Hospital Request an Appointment Request an Appointment For help choosing a doctor or making an appointment, please complete our form or call us directly. (800) 600-3606 I am a: Patient / New Patient Caregiver Physician Menu Prostate Prostate Our Approach to Prostate Cancer Prostate Cancer Specialist Team Prostate Cancer Symptoms Screening for Prostate Cancer Determining Your Prostate Cancer Risk Diagnosis MRI-guided biopsy for prostate Clinical Trials for Prostate Cancer Prostate Cancer Treatment Radiation Therapy for Prostate Cancer Surgery for Prostate Cancer Systemic Therapy for Prostate Cancer Effects of Prostate Cancer Treatment Prostate Cancer Patient Stories Early Detection, Convenient Care Helps Local Man Beat Cancer Screening Leads to Man’s Diagnosis, Survival Local Man Fights Dual Cancer Battle and Wins With Help From Siteman External-Beam Radiation Treatment for Prostate Cancer Our Healthy Men Radio Show National Cancer Institute Information What's on this page The Siteman difference Personal support | Treatment | Cancer Types | Prostate | Our Approach to Prostate Cancer Our Approach to Prostate Cancer Prostate cancer is the most common type of cancer in American men. 1 in 8 men will develop it during their lifetimes. Owing to advances in early diagnosis and effective treatments, the majority of men with prostate cancer will not die from it. Most men begin to suspect they have prostate cancer after obtaining an elevated PSA level or abnormal digital rectal examination. The PSA blood test measures the level of prostate-specific antigen in the blood. The challenge for physicians is determining which patients with high PSA levels need invasive tests such as biopsies, and which patients diagnosed with prostate cancer need localized treatment to the prostate and surrounding tissues, such as surgery or radiation. The Siteman Cancer Center is the only National Cancer Institute-designated Comprehensive Cancer Center in Missouri and is ranked among the top cancer facilities in the nation by U.S. News & World Report. Read more about our mission, vision and history. At Siteman, we diagnose and treat prostate cancer with the most sophisticated imaging techniques, diagnostics, and therapies available. Our multidisciplinary team sees approximately 1,000 new prostate cancer patients a year. Each patient receives an individualized treatment plan for his prostate cancer. Siteman has led the field in the development of genomic testing for personalized, targeted treatment. We were the first institution to sequence the DNA of a cancer patient. Today, we routinely evaluate our patients’ genetic information for additional insights into their cancer. This helps us to better meet every patient’s unique treatment needs. Our research into DNA-based cancer treatments led to the first clinical trial of a “neoantigen” DNA vaccine for metastatic prostate cancer, which targets the specific mutations found in each patient’s tumor in order to stimulate the immune system to fight them. Hear from patients who’ve been treated for prostate cancer at Siteman. Expert physicians Our physicians at Siteman Cancer Center pioneered the prostate-specific antigen (PSA) blood test as a tool for early prostate cancer detection. As laboratory technology has improved, they continue to examine newer blood tests to more accurately determine which patients with an elevated PSA are likely to have an aggressive prostate cancer. They also conducted the world’s largest single-institution prostate cancer screening study with more than 32,000 men and led the NCI-funded PLCO cancer screening trial, which evaluated genetic data from 80,000 men. Meet the team Accurate, customized diagnostic techniques Washington University Physicians at Siteman use cutting-edge tests to evaluate each patient’s level of risk and ensure that he gets the right diagnosis. We pride ourselves on our advanced use of imaging to assess patient risk, and often pair MRI scans with biopsies to ensure that we are finding the worst part of the cancer. In fact, we are one of the few centers in the U.S. who have published a number of studies demonstrating the benefit of prostate MRIs as a diagnostic tool. We also have trials for leading-edge imaging methods, such as PSMA and other PET/CT scanning techniques. In addition, our urologists are working to pair imaging with biomarker tests for maximum accuracy.  Biomarkers are traces of disease than can be present in the blood or urine. They help physicians gauge the severity of your prostate cancer, and can potentially be used to predict how different therapies will work for you. Investigators at Siteman are developing novel “liquid biopsy” tests to determine which patients will respond best to certain prostate cancer drugs. Learn more about the diagnostic process at Siteman. Low-intervention treatment options The Washington University urologists at Siteman know that not every patient with prostate cancer needs to be treated. Instead, some patients with lower-risk prostate cancer can be monitored carefully. This type of close monitoring is called active surveillance. Some patients on active surveillance at Siteman may be eligible to join a clinical trial for immunotherapy, which offers an additional level of treatment. In other patients with prostate cancer, it isn’t necessary to remove the entire prostate. The newest advance in prostate cancer care is focal therapy, methods of treating the prostate cancer tumor without major surgery. Focal therapy may involve removing only the cancerous part of the prostate, freezing the tumor, or shrinking the tumor with high-intensity ultrasounds. Radiation therapy can also cure prostate cancer in place of surgery. Washington University Physicians at Siteman excel at these techniques. Read about low-intervention treatments for prostate cancer. Innovative surgeries For patients who do need to have their prostates removed, our surgeons and urologists are experts at conducting the operation without damaging the surrounding nerves (a procedure called a nerve-sparing radical prostatectomy). This procedure helps preserve normal urination and sexual function. Washington University surgeons are also experts at robotic prostate removal, laparoscopic prostate removal, and open, or conventional, prostate removal. They have completed thousands of prostate operations, which makes our team one of the most experienced in the United States. Patients who come to Siteman generally have higher rates of cure and improved physical well-being. Siteman offers many options for prostate cancer surgery. Immunotherapy Prostate cancer patients may also have the opportunity to be treated with immunotherapy, a ground-breaking technique that teaches the immune system to recognize and destroy cancerous cells. At this time, only one immunotherapy is FDA-approved to treat prostate cancer, and it is only used for patients with advanced, metastatic disease. Urologists at Siteman, however, have teamed up with other researchers and clinicians to explore the use of immunotherapy earlier in prostate cancer treatment. Ongoing clinical trials are also investigating the use of immunotherapy and other therapies before surgery. Learn about prostate cancer immunotherapies. Clinical trials Washington University Physicians at Siteman are actively involved in clinical trials that investigate new technology in the accurate diagnosis and successful treatment of prostate cancer. Having your prostate cancer treated at Siteman gives you access to new diagnostic and treatment approaches that are as good as – or potentially better than – current standard therapies available elsewhere. As prostate cancer treatment continues to evolve, it is important that you are treated at a cancer center that has all treatment options available. Siteman will provide the FDA-approved medications and treatments as well as access to the newest therapies for prostate cancer. Explore Siteman’s prostate cancer clinical trials. At Siteman, we understand that excellent cancer care takes a personal touch. Our experienced nurses are specially trained to support cancer patients and will help you cope with your symptoms, treatments, and side effects. We have registered dieticians on staff who can provide guidance about nutrition and suggest ideas for meals and snacks that will taste good as you move through your treatment plan. In addition, patients and family members who desire mental health care can receive free treatment from our team of skilled cancer psychologists. Social workers are also available to meet with patients. Learn more about supportive services at Siteman. For additional information about travel, lodging, parking, and logistics, visit or contact the Barnard Health and Cancer Information Center. Contact 800-600-3606 Email Subscribe for Siteman Updates X-twitter Facebook Youtube Linkedin Instagram Careers Washington University Barnes-Jewish Hospital Locations Washington University Medical Campus West County St. Charles County South County North County Illinois Copyright © 2015 - 2024 All rights reserved.

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